International patterns and trends in the brain cancer incidence and mortality: An observational study based on the global burden of disease

BackgroundBrain cancer is a serious issue in the global burden of diseases. This observational research aimed to assess trends brain incidence and mortality world period 1990–2019.MethodsBrain data were retrieved from Global Burden Disease 2019 study database. The joinpoint regression analysis was done indicence trends: average annual percent change (AAPC) along with its 95% confidence interval (95% CI) calculated.ResultsIn both sexes, highest age-standardized rates found high-income regions (Europe America), while lowest observed African Region. A significant rise males females all regions, one exception significantly decreased trend only among South-East Asia Among countries increased cancer, Cuba experienced most marked increase (AAPC = +5.7% AAPC +5.4% females) +5.5% +5.1% females). that decline mortality, Hungary Greenland showed sexes (equally by −1.0%).ConclusionBrain shows increasing represents priority for prevention further research.